Here is a selection of the largest studies with antioxidant and especially vitamin E
With regard to the prevention, treatment and aftercare of heart and circulatory diseases.
Clicking on the heading leads to the text of the study (in English).
Lee 2005 (USA, women only): Approximately 19,900 women were given 600 IU of natural vitamin E every 2 days for 10 years (ka tocotrienols).
Result: 24% fewer deaths from heart death (statistically significant), 7% fewer heart attacks (statistically not significant), no influence on mortality from cancer, no influence on overall mortality from all causes (but Bielacovic rated 3% higher overall mortality, why?).
Blot 1992 (China): 29,584 people divided into 4 groups received various vitamins at doses of 1-2 times the US recommendations (RDA) for 5 years. One group received beta-carotene vitamin E and selenium.
Result: The group with beta-carotene vitamin E and Selenium had 9% fewer deaths (mainly due to significantly fewer cancer cases, especially gastric cancer). The effect appeared about 1-2 years after starting the supplementation.
Cambridge Heart Antioxidant Study (CHAOS) (England): 2002 people with heart disease received 400-800IU alpha-tocopherol (natural but isolated) or the placebo for about 1 year. All patients received concurrent blood thinners.
Result:
Among the patients who received vitamin E, there were statistically significant increases in the follow-up period (approx. 1.5 years).47% fewer heart attacks on (fatal or non-lethal). However, the total number of deaths was non-significantly higher in the alpha-tocopherol group (27 vs 23; 1.18 [0.62-2.27]; p=0.61).
GISSI 1999 (Italy,after suffering a heart attack): Four groups of 2830 people each received 1g omega-3, 300mg vitamin E, and other placebo.
Result: Among the groups with omega-3diedin the next 3.5 years10-20% lessPeople. The administration of vitamin E(unspecified, probably synthetic)had either a positive or a negative impact.